|
KMID : 0370219790230020063
|
|
Yakhak Hoeji
1979 Volume.23 No. 2 p.63 ~ p.68
|
|
|
Molecular Interacion of Riboflavin and Orotic Acid Derivatives
|
|
유병설/Yu BS
이상종/정서영/김양배/김종국/Lee SJ/Jeong SY/Kim YB/Kim CK
|
|
|
Abstract
|
|
|
|
Biophysical investigation has been carried out for the interaction of riboflavin tetraacetate and an erotic acid derivative to know the binding mechanism between dihydroorotate dehydrogenase and dibydroorotic acid which are concerned with the oxidoreduction in vivo. Infrared and nuclear magnetic resonance spectra were measured for the chloroform solution of riboflavin tetraacetate, erotic acid butyl ester and its same mixture. Orotic acid butyl ester has been found to associate with riboflavin tetraacetate. They form a strong complex with each other. The complex is an 1:2 cyclic hydrogen bonded trimer through the imino and 2-C carbonyl groups of the isoalloxazine ring and the imino groups of the erotic acid derivative.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|